Titlebook: Cell Fusion in Health and Disease; I: Cell Fusion in He Thomas Dittmar,Kurt S. Zänker Book 2011 The Editor(s) (if applicable) and The Autho

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Role of SNAREs in Membrane Fusion,ent on the curvature of the opposing bilayers. Electron density map and 3-D topography of the SNARE ring complex, suggests the formation of a leak-proof channel measuring 25 Å in ring thickness, and 42 Å in height. The mechanism of membrane-directed SNARE ring complex assembly, and the mathematical

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Membrane Fusions During Mammalian Fertilization,n or cortical granule exocytosis). The secreted cortical contents modify the zona pellucida, converting it to a state that is unreceptive to sperm, constituting a block to polyspermy. In addition, there is a block at the level of the oolemma (also known as the membrane block to polyspermy).

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Macrophage Fusion and Multinucleated Giant Cells of Inflammation, molecular mechanism of macrophage fusion have revealed it to be a mannose receptor-mediated phagocytic process with participation of the endoplasmic reticulum. Further phenotypic and functional investigations will foster new perspectives on these remarkable multinucleated cells and their physiologi

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Cell-Fusion-Mediated Reprogramming: Pluripotency or Transdifferentiation? Implications for Regeneraes of autologous somatic cells to maintain, replace or rescue different tissues has provided new and fundamental insights in the stem-cell-therapy field. Most interestingly, the concept that cell reprogramming can also occur in vivo by spontaneous cell fusion events is also emerging, which suggests

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0065-2598 progression. Thus, Cell Fusion in Health and Disease Vol 1 & Vol 2 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion and beyond.978-94-007-3571-2978-94-007-0763-4Series ISSN 0065-2598 Series E-ISSN 2214-8019

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