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Titlebook: Cell Engineering; Apoptosis Mohamed Al-Rubeai,Martin Fussenegger Book 2004 Springer Science+Business Media B.V. 2004 Mammalia.Regulation.Ti

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楼主: Lipase
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Apoptosis in Hepatocytes,eed, several small molecule caspase inhibitors have been undergoing trials for treatment of liver disease (Whelan ., 2002) and no doubt some will be available soon. Of course the possible targets for such therapy are many in a process so complex.
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The Role of Caspases in Apoptosis and Their Inhibition in Mammalian Cell Culture,applied in conjunction with improvements in bioreactor design, culture medium, cell line development, and expression vector design, optimum biopharmaceutical yield will be possible. Such advancements may lead to a more cost-effective biotechnology operation with recombinant protein yields surpassing those previously obtained.
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A Systems View of Cell Death,ation. The impact of FLIP synthesis upon the activation of executioner caspase was simulated. It was shown that while FLIP synthesis will slow executioner caspase activation, it will not stop it. The model predicts there will always be some activation of procaspase-8 as FLIP binding is reversible..S
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