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Titlebook: Cell Division Machinery and Disease; Monica Gotta,Patrick Meraldi Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusi

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书目名称Cell Division Machinery and Disease
编辑Monica Gotta,Patrick Meraldi
视频videohttp://file.papertrans.cn/223/222807/222807.mp4
概述Reviews the current knowledge to critically evaluate the causal link between cell division machinery and disease.Identifies key open questions in the field and means for exploring them.Explores cell d
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Cell Division Machinery and Disease;  Monica Gotta,Patrick Meraldi Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusi
描述.This book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal link between key elements of the cell division machinery and diseases such as cancer, neuropathologies, aging, and infertility. A more clinically oriented chapter further discusses the current and future applications of anti-mitotic drugs in these diseases. .Cell Division Machinery and Disease. is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases..
出版日期Book 2017
关键词Centrosomes; Infertility; Mitosis; Neuropathology; Polycystic Kidney Disease; Cell Cycle Analysis
版次1
doihttps://doi.org/10.1007/978-3-319-57127-0
isbn_softcover978-3-319-86083-1
isbn_ebook978-3-319-57127-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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An Overview of Epidemiology and Geneticsryo. Accurate execution of the meiotic cell division to generate a female and a male gamete is required for the generation of healthy offspring harboring the correct number of chromosomes. Unfortunately, meiosis is error prone. This has severe consequences for fertility and under certain circumstanc
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Metabolomics Analysis of OPLL Patientsf cell division, the extent of proliferation and the spatial distribution of mitosis allow the formation of tissues of the right size and with the correct structural organization. All these aspects depend on cell cycle duration, correct chromosome segregation and spindle orientation. The centrosome,
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Metabolomics Analysis of OPLL Patientsstanders in cancer but can accelerate tumourigenesis in the absence of the tumour suppressor p53. Centrosome amplification could indeed actively participate in tumour progression through the induction of chromosome instability, disruption of tissue architecture and promoting cell invasion. Paradoxic
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Optimization Methods in Engineeringget for anticancer therapies since fast proliferation was identified as one of the hallmarks of cancer cells. Despite efforts into developing specific inhibitors for mitotic kinases and kinesins, very few drugs have shown the efficiency of microtubule targeting-agents in cancer cells with paclitaxel
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Opinion Mining in Information Retrievalicient cell material is available and affects the overall rate of cell proliferation. At a very fundamental level, cellular replicative lifespan—defined as the number of times a cell can divide, is a manifestation of cell cycle control. Hence, control of mitotic cell divisions, especially when the c
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