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Titlebook: Cell Cycle Inhibitors in Cancer Therapy; Current Strategies Antonio Giordano,Kenneth J. Soprano Book 2003 Springer Science+Business Media N

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Synthetic Oligopeptides as Cancer Cell Cycle Modulators,In higher eukaryotes, many important biological processes, such as cellular differentiation, apoptosis, embryonic development, and finally cancer onset and progression, are closely related to the modulation of the cell cycle.
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Cdk Inhibitors,plicates its genome, and M phase, in which the cell splits into two daughter cells. It is necessary that these two crucial events are regulated and coordinated to occur in an ordered fashion at precisely the right time (for a review . refs. .). This regulation and coordination results from a combina
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Cell Cycle Control of Transcription at the G1/S Phase Transition,n cycle in response to the multi-directional signals of cell type specific signaling cascades. The parameters that mediate growth control are complex and interdependent, and whether cells grow or cease division reflects the integration of a broad spectrum of positive and negative growth regulatory s
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CDK Inhibitors as Targets of Chemoprevention Agents,astic period. The goal of chemopreventive drug development is to identify safe and effective chemopreventive agents for clinical use .. Agents with chemopreventive potential are tested in preclinical toxicity and pharmacokinetic studies and then moved forward to Phase I, II, and III clinical trials
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