Titlebook: Cell Culture Engineering; Wei-Shou Hu Book 2006 Springer-Verlag Berlin Heidelberg 2006 Biotechnology.Cell Culture.Escherichia coli.biochem

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O. G. Castro,A. M. Ferreira,C. Valecific perfusion rates.Under these conditions, titer increases significantly, approaching the range of fed-batch titers. However,as dilution rate is decreased, a limit is reached below which performance declines due to poor growthand viability, specific productivity, or product instability. To overco

Fillet,Filet

CREST

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侵略者

Fedbatch Culture and Dynamic Nutrient Feeding,process engineering willlikely require a combination of current process engineering strategies along with a better understandingand control over cell physiology. Process development will likely to entail not only optimizing traditionalengineering parameters but also engineering cell lines with desir

Monotonous

苦涩

Towards Industrial Application of Quasi Real-Time Metabolic Flux Analysis for Mammalian Cell Culturlation of inhibitory metabolites such as lactate. Changes in glucose, lactate and glutamine uptake/productionrates had significant effects on the calculation of other fluxes in the network. Sensitivity analysis ofthese key metabolic fluxes highlighted the need for accurate and reliable real-time sen

极微小

,Engineering Cells for Cell Culture Bioprocessing – Physiological Fundamentals,ineering cells for a more robust process. The concept of physiological homeostasisas a key determinant and its implications on cell engineering is emphasized. Integrating thephysiological perspective with cell culture engineering will facilitate attainment of dream cellswith superlative characterist

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Cell Culture Engineering978-3-540-34007-2Series ISSN 0724-6145 Series E-ISSN 1616-8542