| 书目名称 | Catalytically Active Nucleic Acids |
| 编辑 | Harald Seitz,Frank Stahl,Johanna-Gabriela Walter |
| 视频video | |
| 概述 | Highlights fundamental aspects of nucleic acids enzymes.Addresses methods and applications.Discusses challenges in and prospects for nucleic acid enzyme engineering |
| 丛书名称 | Advances in Biochemical Engineering/Biotechnology |
| 图书封面 |  |
| 描述 | .This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids’ fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes...After the discovery of natural ribozymes – RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds – numerous artificial ribozymes with altered catalytic activities were produced by .in vitro. and .in vivo. selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat...Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamental |
| 出版日期 | Book 2020 |
| 关键词 | RNA G-Quadruplexes; DNAzymes; nucleic acids; Aptazymes; Transcriptome; RNaseP Ribozyme; DNAzyme Engineerin |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-29646-9 |
| isbn_softcover | 978-3-030-29648-3 |
| isbn_ebook | 978-3-030-29646-9Series ISSN 0724-6145 Series E-ISSN 1616-8542 |
| issn_series | 0724-6145 |
| copyright | Springer Nature Switzerland AG 2020 |
发表于 2025-3-21 17:18:37
