Titlebook: Cartilage; Volume 3: Repair Str Susanne Grässel,Attila Aszódi Book 2017 Springer International Publishing AG 2017 biomaterial.mesenchymal s

有权威

Globalization and It: Agenda for Researchdrocyte transplantation, also large-sized chondral defects can be successfully addressed. This chapter gives a short overview about current procedures for cell-based treatment strategies like bone marrow stimulation techniques, osteochondral transplantation, and chondrocyte transplantation. Requirem

故意

Göran Goldkuhl,Annie Röstlinger,Ewa Brafurgical intervention can address chondral defects and yield positive functional outcomes, substantial research has gone into the use of growth factors to augment cartilage repair and preclude or postpone the need for operative management. This chapter describes the growth factors with the most promi

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guardianship

Jose Esteves,Joan Pastor,João Carvalhothe subchondral bone often precede cartilage destruction in the development of the disease. Integration of the so far published data including in vitro, in vivo, and mathematical work suggests a critical role for this tissue in nutrition and oxygen supply to the articular cartilage, which may become

从容

https://doi.org/10.1007/978-0-387-35695-2ge injury resulting from acute trauma or during osteoarthritis. The focus of this chapter is to examine the benefits of gene therapy to improve cartilage repair in such lesions, based on promising experimental and clinical evidence in relevant models in vivo using growth, transcription, and signalli

Exterior

Emílio Luís Mosse,Sundeep Sahaymmarizes several promising options to engineer articular cartilage-like constructs, ranging from applying biological factors and/or mechanical, magnetic, or even electrical stimuli. The paradigm of cartilage tissue engineering classically comprises three pillars: cells, scaffolds, and signals. As ce

节约

Jens Kaaber Pors,Jesper Simonsen. Such animal models need to reflect the different appearances and aetiologies of cartilage defects, e.g. caused by trauma or osteoarthritis. Depth of articular cartilage defects plays an important role. Full-thickness chondral defects do not extend into the subchondral bone, while osteochondral def

拒绝

https://doi.org/10.1007/978-3-319-53316-2biomaterial; mesenchymal stem cells; osteochondral repair; regenerative tissue engineering; transplant