Titlebook: Cardiovascular System; Robin G. Shanks Textbook 1980Latest edition Macmillan Publishers Limited 1980 cardiovascular.cardiovascular system.

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Use of M-Mode Echocardiography in Clinical Pharmacology,nd its use in the study of left ventricular disease has been described in a number of recent monographs and reviews (Feigenbaum, 1976; Roelandt, 1977; Mason and Fortuin, 1978). It allows a number of aspects of left ventricular function to be studied. Of these, the simplest is the measurement of the

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Non-Invasive Assessment of the Effects of Drugs on Acute Myocardial Infarct Size in Man,ion (Braunwald, 1976; Sobel, Bresnahan, Shell & Yoder, 1972). Experiments, however, indicate that several drugs given early after the occlusion can substantially alter final infarct size. Clinical assessment of the effects of these drugs poses difficulties and an awareness of the limitations of exis

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https://doi.org/10.1007/978-0-387-68805-3ared, but it must be stressed that this simplicity is only apparent, and may conceal complex underlying changes in circulatory state. Furthermore, although left ventricular disease and drug administration have similar effects on the systolic time intervals, there is much evidence to suggest that the

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https://doi.org/10.1007/978-0-387-68805-3s in the biological determinants of drug disposition (Wilkinson, 1975; Wilkinson and Shand, 1975). In addition, as surgeons started to treat portal hypertension occurring in liver disease such as cirrhosis by portocaval or similar anastomoses, liver blood flow was assessed with other parameters of l

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Use of M-Mode Echocardiography in Clinical Pharmacology,eptal movement to be studied. In addition, it is totally safe, so that it can be used on normal volunteers. Performing echocardiography, however, is difficult, and at least 6 months’ practice is likely to be required before records of adequate technical quality are obtained.