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Titlebook: Cardiovascular Pharmacology of 5-Hydroxytryptamine; Prospective Therapeu P. R. Saxena,D. I. Wallis,P. Bevan Book 1990 Springer Science+Busi

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Abelian Groups, Lattices, and Finite Fieldslic inhibitors and by certain selectively-acting compounds. These observations indicate the presence of specific carrier or transport systems involved in the active transport of 5-HT into specific tissue elements.
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https://doi.org/10.1007/978-0-387-49923-9htward shift of the concentration-effect curve and a depression of maximum responses to 5-HT which cannot be surmounted by increased concentrations of 5-HT. However, in some cases, the unsurmountable action of one antagonist can be prevented or reversed by exposure to another, surmountable antagonist.
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Remarks on multiplicative functions,]. When infused into the carotid artery, it reduces cerebral blood flow in many brain regions, provided the blood-brain barrier is opened or monoamine oxidase is inhibited. The response seems to be partly associated with a decrease in cerebral metabolism [9–11].
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The distribution and biochemistry of 5-hydroxytryptamine in the cardiovascular systemn lung, kidney, spleen, thyroid, mast cells, heart and blood vessels of different species. It is well accepted that 5-HT has a role as a neurotransmitter in the brain and as a precursor of melatonin in the pineal gland; its precise function in the other tissues in which it is present has yet to be elucidated.
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Allosteric modulation of arterial 5-HT2 receptorshtward shift of the concentration-effect curve and a depression of maximum responses to 5-HT which cannot be surmounted by increased concentrations of 5-HT. However, in some cases, the unsurmountable action of one antagonist can be prevented or reversed by exposure to another, surmountable antagonist.
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An analysis of unsurmountable antagonism to 5-hydroxytryptamine in the isolated perfused rat kidney:stances of unsurmountable antagonism, to discuss possible mechanisms involved, and to present data suggesting that pseudoirreversible antagonism best explains unsurmountable antagonism of 5-HT-induced vasoconstriction in the isolated perfused rat kidney. Finally, the utility of antagonist probes for receptor classification will be discussed.
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Developments in Cardiovascular Medicinehttp://image.papertrans.cn/c/image/221973.jpg
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