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Titlebook: Cardiovascular Disease, Volume 2; Molecular Medicine Qing K. Wang Book 2007 Humana Press 2007 Microarray.Proteomics.bioinformatics.cardiova

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Animal Models for Heart Failure,ents, why HF develops is still poorly understood. Investigators still seek a truly appropriate animal model that will reliably mimic human HF, so that the cause of the disease can be targeted and proper therapeutic modalities implemented. HF is a complex condition in which multiple molecular mechani
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Optical Mapping of Shock-Induced Arrhythmogenesis in the Rabbit Heart With Healed Myocardial Infarcon research tools in basic cardiac electrophysiology. Significant advantages of this approach include simultaneous noncontact recording of entire action potentials free of electrical stimulus-induced artifacts from multiple closely adjacent sites, and adjustable spatial and temporal resolutions. In
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Methods for Studying Voltage-Gated Sodium Channels in Heterologous Expression Systems,erologous expression) has greatly impacted the field of ion channel physiology. With the addition of site-directed mutagenesis techniques, the functional consequences of virtually any mutation can now be specifically and easily assessed. Here, we describe an effective procedure for investigating car
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Methods for Isolation of Endothelial and Smooth Muscle Cells and In Vitro Proliferation Assays,ex morphogenetic process involving the coordinate migration, invasion, and reorganization of several cell types including endothelial cells, pericytes, smooth muscle cells, and stromal fibroblasts. The angiogenic response begins with excess protease secretion to facilitate basement membrane remodeli
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Murine and HIV-Based Retroviral Vectors for In Vitro and In Vivo Gene Transfer,troviral-based vectors, notably those derived from Moloney murine leukemia virus (MLV) and lentiviral vectors derived from HIV, have proven to be valuable gene transfer vehicles as a result of their ease of production and their ability to mediate long-term transgene expression. One of the most widel
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