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Titlebook: Cardioprotection Against Acute Myocardial Infarction; Shinya Minatoguchi Book 2019 Springer Nature Singapore Pte Ltd. 2019 Acute myocardia

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发表于 2025-3-21 19:12:16 | 显示全部楼层 |阅读模式
书目名称Cardioprotection Against Acute Myocardial Infarction
编辑Shinya Minatoguchi
视频video
概述Helps readers to understand both the mechanism of cardioprotection and tools for cardioprotection after myocardial infarction.Describes treatments including pharmacological pre- and post-conditioning,
图书封面Titlebook: Cardioprotection Against Acute Myocardial Infarction;  Shinya Minatoguchi Book 2019 Springer Nature Singapore Pte Ltd. 2019 Acute myocardia
描述This book will provide readers with a detailed understanding of the ischemic damage to the  myocardium after myocardial infarction, as well as essential tools for the treatment of damaged heart after myocardial infarction. It discusses various methods such as pharmacological pre- and post-conditioning, cytokine therapy, and cell therapy especially using Muse cells.The coverage of Muse cell therapy, which includes the latest work done by the author and his collaborators, is a unique feature of the book. Muse cells have self-renewability and have ability to differentiate into cells with the characteristics of all three germ layers from a single cell, while they are non-tumorigenic. It is the first book to feature the Muse cell therapy, which may offer the new promising therapeutic strategy for acute  myocardial infarction. .
出版日期Book 2019
关键词Acute myocardial Infraction; Cardioprotection; Cell therapy; MSC; Mesenchymal stem cells; Muse cell; Myoca
版次1
doihttps://doi.org/10.1007/978-981-15-0167-8
isbn_softcover978-981-15-0568-3
isbn_ebook978-981-15-0167-8
copyrightSpringer Nature Singapore Pte Ltd. 2019
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发表于 2025-3-21 21:00:07 | 显示全部楼层
Ischemic Preconditioning,s termed as ischemic preconditioning (PC). PC is a powerful endogenous protection and has been demonstrated in dogs, pigs, rabbits and rats and humans. This protection is characterized as a reduction of infarct size and an improvement of postischemic cardiac dysfunction.
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Ischemic Postconditioning,g which is conducted before the onset of ischemia, postconditioning is performed after reperfusion. This protection is characterized as a reduction of infarct size and an improvement of postischemic cardiac dysfunction.
发表于 2025-3-22 09:31:40 | 显示全部楼层
Pharmacological Postconditioning, in reduction of the infarct size and improvement of the cardiac function, such drugs are very valuable in treating the damaged heart after the onset of AMI. However, very few drugs show a pharmacological postconditioning effect. Granulocyte colony stimulating factor (G-CSF), free radical scavengers
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Cytokine Therapy,administration of G-CSF reduced the infarct size and improved the cardiac function through regeneration of cardiomyocytes and vessels, and accelerating the healing process. Post-infarct treatment with an erythropoietin-gelatin-hydrogel sheet or intravenous administration of erythropoietin (EPO)-enca
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Stem Cell Therapy,ainst AMI because animal studies using these cells showed beneficial effects. However, clinical trials using BM-MNCs and MSCs demonstrated their safety but their beneficial effects were small in patients with AMI. Therefore, a new cell source is required for stem cell therapy. Muse cells showed grea
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