Titlebook: Cardiac Safety of Noncardiac Drugs; Practical Guidelines Joel Morganroth (Chief Scientist, Clinical Profess Book 2005 Humana Press 2005 cli

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demonstrating the fundamentals of ECG interpretation in clinical trials, the statistical analysis plans for ECG data obtained in formal clinical trials, and the practical interpretation of the 978-1-61737-612-2978-1-59259-884-7

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Book 2005val. Additional chapters comprehensively review the application of electrocardiology in clinical research, demonstrating the fundamentals of ECG interpretation in clinical trials, the statistical analysis plans for ECG data obtained in formal clinical trials, and the practical interpretation of the

Introduction

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Conclusion: The Liminal Raconteur,ce of central ECG laboratories in measuring ECG intervals on Holter is limited. Pharmaceutical sponsors and patients alike would benefit if reliable QT/QTc assessment were possible by Holter ECG, whereby the continuous ambulatory digital 12-lead ECG would be used to substitute for standard resting s

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Molecular Physiology of Ion Channels That Control Cardiac Repolarizationduration of the action potential plateau (phase 2), which depends on the balance of inward (Ca. and Na.) currents and outward (K.) currents. The main contributor of inward current during the plateau phase is Ca. influx through high threshold, L-type voltage-gated Ca. (Cav) channels. The (L-type Ca.)

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