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Titlebook: Cardiac Glycosides 1785–1985; Biochemistry — Pharm Erland Erdmann,K. Greef,J. C. Skou Conference proceedings 1986 Springer-Verlag Berlin He

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书目名称Cardiac Glycosides 1785–1985
副标题Biochemistry — Pharm
编辑Erland Erdmann,K. Greef,J. C. Skou
视频video
图书封面Titlebook: Cardiac Glycosides 1785–1985; Biochemistry — Pharm Erland Erdmann,K. Greef,J. C. Skou Conference proceedings 1986 Springer-Verlag Berlin He
描述The bicentenary of William Withering‘s now famous medical report entitled "An Account of the Foxglove and Some of its Medical Uses" has given us the occasion to analyze the state of the art. Cardiac glycosides in 1985 are considered tobe the basis for medical treatment of myocardial failure, together with diuretics and vasodilators in the more severe cases. Nevertheless, the controversy as to their exact place in the treatment of heart failure with sinus rhythm has never ceased. Although cardiac glycosides are of unquestionable value in tachycardia caused by atrial fibrillation or atrial flutter, the chronic use of these drugs in sinus rhythm is not generally accepted. The development of tolerance has been reported. It is of interest that Withering hirnself wrote: "-let it (foxglove) be continued until it either acts on the kidneys, the stomach, the pulse, or the bowels; Iet it be stopped upon the first appearance of any of these effects, and I will maintain that the patient will not suffer from its exhibition, nor the practitioner be disappointed in any reasonable expectation. " In West Germany alone, more than three million patients (about 5% of the total population) are constant
出版日期Conference proceedings 1986
关键词anesthesia; artery; atrial fibrillation; drugs; electrocardiogram (ECG); heart; heart disease; heart failur
版次1
doihttps://doi.org/10.1007/978-3-662-11292-2
isbn_softcover978-3-662-11294-6
isbn_ebook978-3-662-11292-2
copyrightSpringer-Verlag Berlin Heidelberg 1986
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Nonconvex Optimization and Its Applicationsh cannot be studied at physiological concentrations of Mg.. By using reconstituted human red cell ghosts containing ATP and little Mg., it is possible to evaluate the side-specificity of those effects of Na. and K. which have been observed in porous ghosts. Some of the following data are detailed in previous papers (5, 6).
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Binding and release of ouabain at low Mg2+ in reconstituted human red blood cell ghostsh cannot be studied at physiological concentrations of Mg.. By using reconstituted human red cell ghosts containing ATP and little Mg., it is possible to evaluate the side-specificity of those effects of Na. and K. which have been observed in porous ghosts. Some of the following data are detailed in previous papers (5, 6).
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Proximal Calculus in Hilbert Space,ort account of the development of the knowledge on digitalis effects, which was based on older similarly formed ideas like those in the German literature; the historical reports by Horst Wirth, Günther Baumgarten and Werner Förster, not to mention other very important papers in the English speaking literature.
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Jiři Outrata,Michal Kočvara,Jochem Zowessociation constants are seen to fit the experimental points well..Ouahain binding data obtained before and after treatment of Na,K-ATPase from ox brain with pyrithiamin are thus compatible with a model assuming two independent populations of receptors (and thus enzymes) in this preparation.
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