Titlebook: Cardiac Cytoarchitecture; How to Maintain a Wo Elisabeth Ehler Book 2015 Springer International Publishing Switzerland 2015 Actin and Myosi

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Elisabeth EhlerGives a concise and comprehensive overview of cardiac cytoarchitecture.Treats the different subcellular compartments of the cardiomyocyte.Addresses development, disease and basic cell biological quest

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978-3-319-34653-3Springer International Publishing Switzerland 2015

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The M-Band: Not Just Inert Glue but Playing an Active Role in the Middle of the Sarcomere,ering active contractile force, the M-band is the origin of signalling processes that can go all the way to the nucleus to affect gene transcription. The mechanical deformations of the M-band filaments during muscle contraction allow the integration of smart molecular sensors to monitor the activity

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The Nuclear Envelope in Cardiac Health and Disease,ns to these components result in disease phenotypes, which vary in severity and tissue specificity and are often broadly termed ‘premature ageing disorders’. One of the key phenotypes frequently present is cardiomyopathy. As a result, the NE is becoming increasingly relevant in the context of cardia

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https://doi.org/10.1007/978-3-540-68430-5thick myosin filaments and thin actin filaments that slide past each other and shorten the sarcomere in response to an action potential. Because all sarcomeres within a cell are aligned, and all cells in a tissue are aligned, the amount of uniaxial force generated by the tissue as a whole is maximiz