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Titlebook: Cardiac Arrhythmias: New Therapeutic Drugs and Devices; Proceedings of the S Joel Morganroth,E. Neil Moore Conference proceedings 1985 Mart

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书目名称Cardiac Arrhythmias: New Therapeutic Drugs and Devices
副标题Proceedings of the S
编辑Joel Morganroth,E. Neil Moore
视频video
丛书名称Developments in Cardiovascular Medicine
图书封面Titlebook: Cardiac Arrhythmias: New Therapeutic Drugs and Devices; Proceedings of the S Joel Morganroth,E. Neil Moore Conference proceedings 1985 Mart
描述In summary, there are many animal models that are useful in selecting new antiarrhythmic drugs. The selection of which model is most idea depends upon precisely what question is being asked. The large number of experimental models used to evaluate antiarrhythmic compounds points out the inability of anyone model to define the probability of antiarrhythmic efficacy in man. It has therefore become standard practice to utilize a batter of animal models for the evaluation of new antiarrhythmic agents. Each model has its own advantages and disadvantages and it is necessary to understand each model fully in oder to evaluate experimental findings and apply them to clinical settings. We believe that the availability of the chronic myocardial infarction ventricular tachyarrhythmia model provides 1) an excellent opportunity to more precisely understand arrhythmia mechanisms, 2) to develop new techniques such as signal averaging for evaluating late low level potentials identifying hearts at high risk of sudden death 3) to identify new antifibrillatory drugs versus drugs that are effective primarily against PVC‘s and ventricular tachycardia 4) to identify new surgical techniques to eliminate V
出版日期Conference proceedings 1985
关键词arrhythmia; drug; drugs; heart; heart disease; myocardial infarction; research; sudden cardiac death
版次1
doihttps://doi.org/10.1007/978-1-4613-2595-6
isbn_softcover978-1-4612-9626-3
isbn_ebook978-1-4613-2595-6Series ISSN 0166-9842
issn_series 0166-9842
copyrightMartinus Nijhoff Publishing, Boston 1985
The information of publication is updating

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https://doi.org/10.1007/b138648units. and from chance events captured on dynamic ECG recorders. show that ventricular tachyarrhythmias (ventricular tachycardia, ventricular flutter and ventricular fibrillation) are the commonest arrhythmias implicated.
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Conservation Laws and Shock Waves,The clinical reviewer for New Drug Applications (NDA) or Investigational New Drug Exemptions (IND’s) is faced with the sheer weight of the applications and NDA submissions have gone well above 1,000 volumes in size. Since each volume is about 500 pages long, this is about one half million pages to review.
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Use of a Computer in the New Drug Evaluation ProcessThe clinical reviewer for New Drug Applications (NDA) or Investigational New Drug Exemptions (IND’s) is faced with the sheer weight of the applications and NDA submissions have gone well above 1,000 volumes in size. Since each volume is about 500 pages long, this is about one half million pages to review.
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