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Titlebook: Cardiac Arrhythmias: New Therapeutic Drugs and Devices; Proceedings of the S Joel Morganroth,E. Neil Moore Conference proceedings 1985 Mart

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Nonlinear Diffusion-Reaction Phenomena,in much the same way as it might be used in medical practice. A design and analysis which parallel the expected clinical use of the drug might be seen as lessening the problems of extrapolation which so often arise after a clinical trial is completed. However, this desire to mimic clinical practice
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Conservation Laws and Shock Waves,brillation (VF). Routine clinical evaluation usually reveals ample evidence for the existence of heart disease in patients with these arrhythmias. Coronary heart disease is by far the most frequently occurring etiologic form of heart disease (about 80%) followed by cardiomyopathy and valvular heart
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0166-9842 pends upon precisely what question is being asked. The large number of experimental models used to evaluate antiarrhythmic compounds points out the inability of anyone model to define the probability of antiarrhythmic efficacy in man. It has therefore become standard practice to utilize a batter of
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What Animal Models are Useful in Selecting New Antiarrhythmic Drugs?ening” for a new active compound or alternatively, “evaluating” an already identified active antiarrhythmic drug. This paper will deal primarily with models designed to evaluate mechanisms of action and effectiveness of new antiarrhythmic agents.
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