Titlebook: Cardiac Allograft Rejection; G William Dec,Jagat Narula (Director),Ignasi Carri Book 2001 Springer Science+Business Media New York 2001 Im

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New Immunosuppressive Agentscuses on those small molecules that have shown to have immunosuppressive activity in patients. (Fig.1). Two monoclonal antibodies are also included as examples of a resurgence of development in this area.

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lved from an unproven experimental surgicaltechnique to the most effective form of therapy for refractoryend-stage heart disease. It has captured the public‘s imagination andexpanded our understanding of fundamental immunologic mechanisms thatare responsible for cellular and humorally-mediated immun

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P. Veltri,F. Malara,L. Primaveraovations in managing acute rejection and infection, particularly cytomegalovirus (CMV) infection. Despite the substantial improvement in early survival, the long-term survival rate has not increased during the past decade.

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Holm Altenbach,Marco Amabili,Yuri V. Mikhlinnd 1.3 at 3, 6, and 12 months post-transplant, repectively (Figure 1A).. Actuarial freedom from first treated rejection episode was 39% at 6 months and 37% at 12 months (Figure IB). Overall, more than 90% of all rejection episodes occur in the first six months post-transplant..

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Nonlinear Mechanics of Complex Structuresensive, time-consuming and not 100% sensitive since sampling error may occur. These limitations have createda need for developing an inexpensive, non-invasive methods to assess the entireallograft for rejection and to follow its response to therapy

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Endomyocardial Biopsy Diagnosis of Cardiac Allograft Rejectionptomes made endomyocardial biopsy safer and more widely used, becoming a valuable tool in the diagnosis of cardiac diseases.. It also introduced a working link between the pathologist and clinical cardiologist..