Titlebook: Cannabis and Cannabinoid-Based Medicines in Cancer Care; A Comprehensive Guid Claude Cyr,Mellar P. Davis,Paul Daeninck Book 2022 Springer N

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Overview of the Endocannabinoid System and Endocannabinoidome,ve or negative. There are now several orphan receptors which have been determined to interact with cannabinoids, including GPR3, GPR6, GPR12, GPR18, GPR55, and GPR119. It has been therefore proposed to name this expanded endocannabinoid system the ., which would better reflect the multisystem influe

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Cannabinoid-Based Medicine: Pharmacology and Drug Interactions,ctions are largely inhibitory in nature and encountered through the CYP2C family. Other drug interactions via immunomodulatory mechanisms have been shown to reduce efficacy of check-point inhibitors and are a reminder that cannabis use should be closely monitored in cancer patients.

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Cannabinoid-Based Medicines as Cancer Therapy,dicines to treat cancer. Little is known in terms of dosing and choice of cannabinoid formulation, and potential risks have also recently emerged which could reduce the efficacy of certain novel cancer treatments, such as immune checkpoint inhibitors, and may theoretically increase tumor progression

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Choosing a Product, Route of Administration, Initial Dosage, Titration, Monitoring and Management os, suppositories, etc. Most patients will benefit from oral or oromucosal administration for baseline administration, while inhaled cannabis is reserved for breakthrough or episodic symptoms in specific clinical settings..The main active ingredients of cannabis are THC and CBD, which have their own

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Psychoactive Effects of Cannabinoid-Based Medicines: Exploration and Inquiry, mid-nineteenth century suggest that cannabis-induced altered states of consciousness can be encountered at higher doses and are similar in nature to the effects produced by LSD or psilocybin. It has been hypothesized that traditional psychedelic compounds disrupt neural networks as a result of inte

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Robert Kastenbaum,Philip E. Slatertments. Thus, extrapolated data from preclinical research and observational studies does not yet translate to established clinical benefits, and until further data confirms these preliminary findings, the use of cannabis in cancer care should be regarded as a multimodal treatment option in order to increase the likelihood of clinical benefits.

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