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Titlebook: Cancer Therapy; Monoclonal Antibodie Hans G. Beger (Professor of Surgery),Markus Büchle Conference proceedings 1989 Springer-Verlag Berlin

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J. I. Sprent,F. R. Minchin,R. Parsonsthe treatment of advanced melanoma in 24 patients [1]. In this report, we present results on the first 30 patients treated with this regimen. Our rationale for giving low-dose CY was to inhibit suppressor T cells, the number and activity of which might be increased by IL-2, thereby possibly preventi
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New Horizons in Occultation Researchferentiation and mature myeloid cell function. With the availability of large quantities of these agents in recombinant form [1–4], it was soon demonstrated that they could as well increase the rate of myeloid cell proliferation in vivo and increase blood myeloid cell numbers [5–8]. The most obvious
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New Horizons in Occultation Research of cancer, particularly since in 1981 highly purified material produced by recombinant DNA technology has become available in addition to natural IFNs [25, 51, 59]. So far, the most impressive clinical results have been achieved in hematologic disorders, especially in hairy cell leukemia [26, 41, 5
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New Horizons in Occultation Researchkes stages, the 5-year-survival rates never exceeded 50% [1, 2]. Surgical progress has been restricted to the development of sphincter-saving procedures for rectal cancer at low levels [3–6]. However, an improvement in the prognosis of colorectal cancer patients should not be expected from surgery a
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J. I. Sprent,F. R. Minchin,R. Parsonsng an increase in the number of helper and cytolytic T cells and in lymphokine-activated killer (LAK) cells as well. The dose of IL-2 was chosen to be at or near the projected maximum tolerated single dose level, as estimated from Phase I data.
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Conference proceedings 1989nd radiotherapy with new approaches in the field of immunotherapy can result in an improved treatment modality. Immunotherapy in this context consists of therapy with monoclonal antibodies, hematopoietic growth factors and other lymphokines. Results of early clinical trials with IL-2, GM-CSF and mon
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