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Titlebook: Cancer Systems Biology, Bioinformatics and Medicine; Research and Clinica Alfredo Cesario,Frederick Marcus Book 2011 The Editor(s) (if appl

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发表于 2025-3-21 17:05:54 | 显示全部楼层 |阅读模式
书目名称Cancer Systems Biology, Bioinformatics and Medicine
副标题Research and Clinica
编辑Alfredo Cesario,Frederick Marcus
视频videohttp://file.papertrans.cn/222/221207/221207.mp4
概述The world’s top experts describe systems approaches to cancer research and application.Is uniquely organized to unify all aspects from laboratory to clinic.Demonstrates how systems approaches build up
图书封面Titlebook: Cancer Systems Biology, Bioinformatics and Medicine; Research and Clinica Alfredo Cesario,Frederick Marcus Book 2011 The Editor(s) (if appl
描述.This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods.  Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of avai
出版日期Book 2011
关键词Bioinformatics; Cancer; Systems Biology; Systems Medicine
版次1
doihttps://doi.org/10.1007/978-94-007-1567-7
isbn_softcover978-94-017-8365-1
isbn_ebook978-94-007-1567-7
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 201
The information of publication is updating

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Cancer: Clinical Background and Key Challengesystems approaches to the pathology and treatment of cancer. In particular, it addresses diagnosis and therapy by interconnecting various aspects of cancer at both the molecular and clinical level, and contrasts the unifying features of malignancies with the daunting diversity of cancer types, stages
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Global Molecular and Cellular Measurement Technologiesencing field where capacity and throughput have increased by several orders of magnitude. This has been a major factor in systems biology research, which thrives on technologies facilitating efficient and relatively economical genome-wide readout on DNA, mRNA, protein, and metabolome level. With dat
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Computational Tools for Systems Biologyiew of the available tools and methods. The reader is familiarised with the development of standards in computational systems biology regarding description and annotation of models, methods, and data standards which enable communication between different groups working in the same field and permit a
发表于 2025-3-23 02:57:03 | 显示全部楼层
The Hallmarks of Cancer Revisited Through Systems Biology and Network Modellingnvestigations, new systems-based approaches have provided a wide range of improved investigative methods. These approaches integrate various global data types into mathematical and computational models of molecular and cellular pathways and networks that become dysregulated in cancer, since the mode
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Systems Biology Analysis of Cell Death Pathways in Cancer: How Collaborative and Interdisciplinary Rlation in this genetically-regulated process plays an important role in the pathophysiology of different disorders. Excessive cell death is pathogenic when it concerns post-mitotic cells and results in various diseases, such as infarction, stroke or neurodegenerative disorders. Insufficient cell dea
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