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Titlebook: Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology; Sadegh Babashah Book 2015 Springer International P

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书目名称Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology
编辑Sadegh Babashah
视频video
概述Introduces emerging concepts in cancer stem cell biology and advances our understanding of potential cancer stem cell-based approaches for the development of therapeutic strategies in oncology.Provide
图书封面Titlebook: Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology;  Sadegh Babashah Book 2015 Springer International P
描述The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.
出版日期Book 2015
关键词Cancer stem cells; Chemoresistance; Stem cell pathways; Therapy; Translational studies; antibacterial dru
版次1
doihttps://doi.org/10.1007/978-3-319-21030-8
isbn_softcover978-3-319-36393-6
isbn_ebook978-3-319-21030-8
copyrightSpringer International Publishing Switzerland 2015
The information of publication is updating

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Masato Shibuya,Yoshitaka Oku,Ikuo Hommas that utilize a range of intracellular signaling pathways to communicate this to the nucleus, rapidly impacting on the transcription of target genes in order to elicit the desired response, such as proliferation, differentiation, activation, and survival. Dysregulation of these important signaling
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New Frontiers in Social Innovation Researchm cells (BCSC) are resistant to traditional treatments and able to initiate tumorigenesis, suggesting that they may contribute to therapy resistance and relapse. The expression of specific markers in BCSCs and development of mouse model has facilitated the study and several intrinsic and extrinsic p
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New Frontiers in Social Innovation Researchnosis and high mortality. Breast cancer stem cells are a small group of cells among the bulk of the tumor that shows stem cell properties, like self-renewal and immortality. They are believed to be involved in cancer promotion, development, and have been studied as important molecules either for dia
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