Titlebook: Cancer Stem Cells: Basic Concept and Therapeutic Implications; Farhadul Islam,Alfred K. Lam Book 2023 The Editor(s) (if applicable) and Th

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Cancer Stem Cells in Cancer Initiation and Progression,SCs play an important role in the initiation and progression of cancer, and as such, there has been extensive research into the molecular and cellular mechanisms underlying the properties of CSCs and how they contribute to the development and spread of cancer. CSCs are thought to be responsible for

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Therapeutics Targeting Cancer Stem Cell Signalling Pathways,s. CSCs render conventional therapies, such as chemotherapy and radiation, to be inadequate in several cancer types. Aberrant signalling pathways in these CSCs, which lead to their self-renewal and proliferative capacity, have been an area of research for which cancer therapeutics are targeted again

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Immunotherapy Against Cancer Stem Cells,nt to conventional cancer treatments and are capable of re-establishing disease. While surgery, chemotherapy, and radiotherapy are routine cancer treatments, additional strategies are required to eliminate CSCs. Innovative approaches to target CSCs using immunotherapy are emerging, and studies of th

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Engineering Nanobody Targeting Cancer Stem Cells,ance, and high immunogenicity. Recent studies identified several clinical applications of Nbs targeting various cancers. Cancer stem cells (CSCs) comprise a limited subpopulation of cancer cells that can reproduce autonomously and differentiate into diverse cancer lineages. CSCs are responsible for

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Biological Barriers for Drug Delivery to Cancer Stem Cells,it some exclusive characteristics for cancer initiation and progression (e.g., capable of self-renewal, tumor growth, survival, therapy resistance, invasion, and metastasis). These characteristics of CSCs make them a new and exciting target for cancer therapy. Several small molecules or biological m

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