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Titlebook: Cancer Stem Cells: Basic Concept and Therapeutic Implications; Farhadul Islam,Alfred K. Lam Book 2023 The Editor(s) (if applicable) and Th

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发表于 2025-3-21 16:19:24 | 显示全部楼层 |阅读模式
书目名称Cancer Stem Cells: Basic Concept and Therapeutic Implications
编辑Farhadul Islam,Alfred K. Lam
视频videohttp://file.papertrans.cn/222/221201/221201.mp4
概述Present the role of cancer stem cells (CSCs) in cancer initiation and progression.Discusses therapeutic approaches targeting cancer stem cells.Examines transcription factors that regulate the biologic
图书封面Titlebook: Cancer Stem Cells: Basic Concept and Therapeutic Implications;  Farhadul Islam,Alfred K. Lam Book 2023 The Editor(s) (if applicable) and Th
描述.This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the maintenance and survival of CSCs.  It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity of CSCs in cancer biology. Further, it also presents the implications of CSCs on the origin of tumor heterogeneity and on heterogeneity of the therapeutic response.  Towards the end, this book highlights the different immunotherapeutic approaches targeting CSCs with the potential of strongly improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications..​
出版日期Book 2023
关键词Cancer stem cells; Signaling pathways; Engineering nanobody; Immunotherapy; Cancer initiation
版次1
doihttps://doi.org/10.1007/978-981-99-3185-9
isbn_softcover978-981-99-3187-3
isbn_ebook978-981-99-3185-9
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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ook offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications..​978-981-99-3187-3978-981-99-3185-9
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Takuya Nakashima,Tsuyoshi Kawaiargeting the epigenetic mechanisms which give CSCs the ability to persist through cancer treatment. Epigenetic targeting dugs show promising clinical trial results as they combat the resistant nature of CSCs due to their frequent epigenetic changes.
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https://doi.org/10.1007/978-3-540-69808-1ncer, as it is difficult to eliminate CSCs and prevent the spread of the disease. There is ongoing research into the molecular and cellular mechanisms underlying the properties of CSCs, as well as efforts to develop targeted therapies that specifically target CSCs to improve the treatment of cancer.
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Davide Cerotti,Daniele Codetta-Raiteries to overcome this problem. Briefly, due to the unique characteristics of tumor vasculature, nanomedicines selectively accumulate in tumor tissue avoiding normal tissues, resulting in negligible side effects and exhibit profound tumor selectivity. However, challenges do exist in the development of
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