书目名称 | Cancer Stem Cells: Basic Concept and Therapeutic Implications |
编辑 | Farhadul Islam,Alfred K. Lam |
视频video | http://file.papertrans.cn/222/221201/221201.mp4 |
概述 | Present the role of cancer stem cells (CSCs) in cancer initiation and progression.Discusses therapeutic approaches targeting cancer stem cells.Examines transcription factors that regulate the biologic |
图书封面 |  |
描述 | .This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the maintenance and survival of CSCs. It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity of CSCs in cancer biology. Further, it also presents the implications of CSCs on the origin of tumor heterogeneity and on heterogeneity of the therapeutic response. Towards the end, this book highlights the different immunotherapeutic approaches targeting CSCs with the potential of strongly improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications.. |
出版日期 | Book 2023 |
关键词 | Cancer stem cells; Signaling pathways; Engineering nanobody; Immunotherapy; Cancer initiation |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-99-3185-9 |
isbn_softcover | 978-981-99-3187-3 |
isbn_ebook | 978-981-99-3185-9 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |