Titlebook: Cancer Neurology in Clinical Practice; Neurologic Complicat David Schiff,Santosh Kesari,Patrick Y. Wen Book 2008Latest edition Humana Press

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Leptomeningeal Metastasese increased the ability of the clinician to make this diagnosis and to make therapeutic decisions. The incidence of this disorder will continue to rise as treatments for systemic cancer become more effective. Unfortunately, the prognosis for this illness remains grim even for patients who receive ag

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https://doi.org/10.1007/978-3-031-22765-3 Treatment of metastases to the PNS is generally palliative and includes radiotherapy, chemotherapy, and pain management. The response to therapy is variable and commonly difficult to maintain. Every effort should be made on behalf of the patient to provide satisfactory pain control and to maximize neurologic function and quality of life.

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Skull and Dural Metastases therapy, with doses ranging from 30 to 35 Gy. Surgical resection is appropriate for selected patients with accessible, solitary lesions, especially if there is mass effect. Chemotherapy may be beneficial, alone or in combination with irradiation, for patients with chemosensitive tumors.

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