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Titlebook: Cancer Microenvironment and Therapeutic Implications; Tumor Pathophysiolog Gianfranco Baronzio,Gianfranco Fiorentini,Christop Book 2009 Spr

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发表于 2025-3-21 19:44:01 | 显示全部楼层 |阅读模式
书目名称Cancer Microenvironment and Therapeutic Implications
副标题Tumor Pathophysiolog
编辑Gianfranco Baronzio,Gianfranco Fiorentini,Christop
视频video
概述A bird’s-eye view of cancer biology.A critical appraisal of cancer’s context in addition to its substance.Written by a team of physician-scientists merging experiences at the lab bench with the fight
图书封面Titlebook: Cancer Microenvironment and Therapeutic Implications; Tumor Pathophysiolog Gianfranco Baronzio,Gianfranco Fiorentini,Christop Book 2009 Spr
描述.In the post-genomic era, cancer is a genetic disease. However, cancer genotype does not always equal cancer phenotype. Cancers with the same genetic abnormalities don’t always behave the same. Understanding and eradicating cancers will require an appreciation for cancer’s ecology...This book is the first to comprehensively explore and critically appraise cancer microenvironments and host interactions with an eye towards exploiting our understanding for new treatments. The team of contributors share amongst them impressive experiences at the laboratory bench and in the clinic. These physician-scientists have dedicated themselves to the tension between the urgency for cures and the technical challenges of discovery...The target audience includes clinical oncologists, clinical hematologists, research oncologists, research hematologists, immunologists, stem cell researchers, oncology and hematology fellows (trainees), oncology educators (graduate and undergraduate levels), and course book for graduate students and undergraduate students..
出版日期Book 2009
关键词angiogenesis; cancer; carcinogenesis; cell; chemotherapy; hematology; hyperthermia; inflammation; oncology; p
版次1
doihttps://doi.org/10.1007/978-1-4020-9576-4
isbn_softcover978-90-481-8160-5
isbn_ebook978-1-4020-9576-4
copyrightSpringer Science+Business Media B.V. 2009
The information of publication is updating

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entists merging experiences at the lab bench with the fight .In the post-genomic era, cancer is a genetic disease. However, cancer genotype does not always equal cancer phenotype. Cancers with the same genetic abnormalities don’t always behave the same. Understanding and eradicating cancers will req
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Cancer, Stem Cells and the Neoplastic Niche the proper cancer target. Designing novel therapeutics for cancer eradication will require understanding specific pathways involved in cancer initiating cell self-renewal, differentiation and homing. Furthermore, targeting the distinctions of the cancer initiating cell microenvironment may be key to effective cancer therapies.
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Significance of the Tumour Microenvironment in Radiotherapyly radiosensitising hypoxic cells, or killing them with specific cytotoxins. More recent approaches have concentrated on the tumour vascular supply itself. Many of these hypoxia targeted therapies have shown benefit in clinical trials, but while additional testing is ongoing for some of them, newer agents are continually being developed.
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Targeting Tumour Vascularization from Bench to Bedside: Suggestions for Combination with Hyperthermiis chapter we summarize the state of the art regarding the combination between drugs that targeting tumour vasculature and hyperthermia, furthermore the pre-clinical rationale for future clinical trials is suggested.
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