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Titlebook: Cancer Metastasis; Molecular and Cellul Volker Schirrmacher,Reinhard Schwartz-Albiez Conference proceedings 1989 Springer-Verlag Berlin Hei

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The Role of Macrophages in the Regulation of Tumor Growth and Metastasishese cells is stimulated by the knowledge that macrophages have the potential to kill neo-plastic cells, including drug-resistant variants surviving conventional chemotherapy (Giavazzi et al. 1984; Allavena et al. 1987).
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Metastasis: The Clinical Problems as observed by clinicians, the mechanisms of which could be hypothetically exploited in future therapies, and finally to challenge the researcher/clinician with some of the major problems in metastasis therapy.
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The Nude Mouse Model for Studies of Human Cancer Metastasisected. Second, the location of many metastases limits our ability to selectively deliver therapeutic agents to them without damaging normal tissues. Third, the heterogeneous nature of malignant neoplasms leads to the rapid development of metastases that are resistant to conventional therapies (Poste 1986; Fidler and Balch 1987; Nicolson 1987).
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Genetic Analysis of Invasive and Metastatic Capacity in T Lymphoma Cells of invasion and metastasis and the role of oncogenes in these processes. In our studies we have employed mouse BW5147 T lymphoma cells to analyze the genetic basis of invasion and metastasis of tumor cells by means of transfection experiments and somatic cell fusion studies.
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Metastatic Phenotype and Cell Differentiation in Melanoma Cellsduction of differentiation as a means of reducing malignancy and improving survival has been studied most extensively using haematological tumours, particularly the myeloid and erythroid leukaemias of mice, but the phenomenon can be duplicated in some common solid neoplasms (Bennett et al. 1986).
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Cell Shape and the Metastatic Phenotypeell assumes a number of different morphological configurations varying from densely packed within the tumor mass, deformed and elongated in invasion, and free-floating in the bloodstream. During each of these stages it must acquire distinct functional capabilities requiring the expression of distinct molecular entities.
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Workers’ Management and the Marketected. Second, the location of many metastases limits our ability to selectively deliver therapeutic agents to them without damaging normal tissues. Third, the heterogeneous nature of malignant neoplasms leads to the rapid development of metastases that are resistant to conventional therapies (Poste 1986; Fidler and Balch 1987; Nicolson 1987).
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Towards a Bioarchaeology of Care of Children of invasion and metastasis and the role of oncogenes in these processes. In our studies we have employed mouse BW5147 T lymphoma cells to analyze the genetic basis of invasion and metastasis of tumor cells by means of transfection experiments and somatic cell fusion studies.
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