Titlebook: Cancer Immunology; R. Adrian Robins,Robert C. Rees Book 2001 Springer Science+Business Media Dordrecht 2001 Antigen.immunotherapy.melanoma

欢腾

Recognition of human tumours: cancer/testis antigens,SART-3, TSP50, CT9 and CTp11 antigens. SART-1 and SART-3 antigens are different from the other CT antigens in that they are expressed in some normal non-testes cells on mRNA levels, but the protein product has been detected only in tumour cells and in testes. In this they resemble another tumour ant

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使出神

resuscitation

Anti-idiotypic vaccination,this is a common mechanism for tumours to evade CTL killing it is an important component of any immune response induced by a cancer vaccine. The potential of antibody responses to contribute to anti-tumour effects is less clear. The ‘type 1’ T cells that help in the activation of CTLs can help in th

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Genetically modified tumour cells for cancer immunization, direct delivery of immunostimulatory molecule genes to tumours . also shows some efficacy, especially the suicide gene Herpes Simplex Virus thymidine kinase. Future clinical trials in earlier stage patients will provide the clearest indication of the efficacy of immunization with transduced tumour

漂浮

Escape Mechanisms in Tumour Immunity,wed. Some of the overall concepts have been recently discussed in a “Symposiumin-Writing” published in October 1999 (see ref.[1]). Weight will be given to those studies that not only contribute to defining the nature of the event associated with tumour escape, but point to possible ways for preventi

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