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Titlebook: Cancer Gene Therapy; Past Achievements an Nagy A. Habib Book 2002 The Editor(s) (if applicable) and The Author(s), under exclusive license

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楼主: Denial
发表于 2025-3-25 07:05:36 | 显示全部楼层
https://doi.org/10.1007/978-4-431-68093-2 Adenoviruses are currently the most promising vectors for gene therapy of malignant glioma especially because of their high efficiency of gene transfer. Experiences from preclinical in vitro and in vivo studies are promising and in the near future the first reports of clinical phase I and II studie
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New Advances in Distributed Computer Systemsed investigational gene therapy protocols. Several studies have shown a potential modality of p53 gene transfer in cancer gene therapy. We also developed a new recombinant adenovirus carrying a wild-type p53 gene (AxCAp53). Although the efficacy of AxCAp53 to suppression of cell growth was not suffi
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https://doi.org/10.1007/978-3-031-30247-3f genes can be expressed in an HCC-specific manner under the control of the AFP regulatory sequences . and .. It would appear that, with the development of a suitable delivery system, HCC-directed gene therapy using the AFP regulatory sequences holds a promising future.
发表于 2025-3-26 03:53:21 | 显示全部楼层
Human , Transcriptional Regulatory Sequencesf genes can be expressed in an HCC-specific manner under the control of the AFP regulatory sequences . and .. It would appear that, with the development of a suitable delivery system, HCC-directed gene therapy using the AFP regulatory sequences holds a promising future.
发表于 2025-3-26 05:02:05 | 显示全部楼层
Souvik Sarker,Md. Mujibor RahmanMan has evolved sophisticated defence mechanisms over millions of years to combat insertion of foreign DNA into his cells. However, gene therapy carries huge potential for the treatment of cancer. The challenge is therefore to translate our scien-tific knowledge into a clinical reality.
发表于 2025-3-26 10:54:06 | 显示全部楼层
Management Problems in OncologyMan has evolved sophisticated defence mechanisms over millions of years to combat insertion of foreign DNA into his cells. However, gene therapy carries huge potential for the treatment of cancer. The challenge is therefore to translate our scien-tific knowledge into a clinical reality.
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Vikas Rawat,Shekhar Singh,Mahabir Singh Negigh titers and have level transgene expression are likely to have minimum immunological responses the most common problem associated with adenoviruses. It is encouraging to note that in Phase I clinical trials, first generation adenoviral vectors have been found to be fairly safe.
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