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Titlebook: Cancer Cytogenetics; Methods and Protocol Thomas S.K. Wan Book 2017 Springer Science+Business Media, LLC, part of Springer Nature 2017 Arra

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Cytoplasmic Immunoglobulin Light Chain Revelation and Interphase Fluorescence In Situ Hybridizationc options can be discussed. Owing to the patchy nature of the disease in the bone marrow (BM), the low proliferative activity of plasma cells and the cryptic nature of some PCM-associated cytogenetic changes, karyotypic analysis in this disease should be augmented with targeted interphase fluorescen
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High Resolution Fiber-Fluorescence In Situ Hybridization,probe hybridizing on DNA molecules and chromosomal regions. Since various types of DNA and chromatin fibers can be generated reflecting different degrees of DNA/chromatin packaging status, fiber-FISH technology has been successfully used in diverse molecular cytogenetic/cytogenomic studies. Followin
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Multicolor Karyotyping and Fluorescence In Situ Hybridization-Banding (MCB/mBAND),t approach when thinking about mFISH is multicolor karyotyping using human whole chromosome paints as probes; this can be achieved by narrow-band filter-based multiplex-FISH (M-FISH) or interferometer/spectroscopy-based spectral karyotyping (SKY). Besides, various FISH-based banding approaches were
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Cytogenetics for Biological Dosimetry,erged, but none are as specific as cytogenetic approaches, particularly the dicentric assay. Here, we will focus on the principal cytogenetic techniques used for biological dosimetry: the dicentric assay in metaphase cells, the micronuclei assay in binucleated cells, and the premature condensed chro
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Recurrent Cytogenetic Abnormalities in Acute Myeloid Leukemia,onic myeloid leukemia and other myeloid neoplasms. Recurrent chromosomal translocations such as t(8;21), t(15;17), and inv(16) are frequently detected, but hundreds of other uncommon chromosomal aberrations from AML also exist. This chapter discusses 22 chromosomal abnormalities that are common stru
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