Titlebook: Cancer Chemoprevention; Raymond C. Bergan (Director, Experimental Therapeu Book 2001 Springer Science+Business Media New York 2001 cancer.

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https://doi.org/10.1007/978-3-7091-6377-1dence of many diseases worldwide. The history of immunology actually predates Jenner to ancient China, India and Persia. The observation that recovery from a particular disease rendered people “immune” to a second episode of that same disease, led the Chinese to try to prevent smallpox by exposing u

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Agent Identification and Preclinical Testing,development program of the Division of Cancer Prevention (DCP), National Cancer Institute (NCI) to identify chemical agents or natural biological products which may be efficacious in preventing human cancers. The first step of the drug discovery process involves subjecting candidate agents to a sequ

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Intermediate Biomarkers,d by growth acceleration and further genetic damage (promotion) and, finally, development of malignant tumors (progression) [.]. With the latency period between stages ranging from years to decades, the science of cancer chemoprevention seeks to intervene using relatively nontoxic agents to prevent,

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Tissue Microdissection and Processing,s from a heterogeneous background of non-neoplastic elements such as normal epithelium, desmoplastic stroma, inflammatory cells and blood vessels(.).In the absence of a prior cell enrichment technique, the results of molecular analysis are undoubtedly confounded by genetic material not derived from

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Chemoprevention in Prostate Cancer,eath in approximately 31,900 (.). World wide, these numbers are much higher (.). Even in those who do not die from disease, treatment is associated with significant morbidity (.). There are a number of features particular to prostate cancer which make it an ideal disease model for the development an

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