Titlebook: Cancer Biology and the Nuclear Envelope; Recent Advances May Eric C. Schirmer,Jose I. de las Heras Book 2014 The Editor(s) (if applicable)

maintenance

https://doi.org/10.1007/978-3-662-08957-6utation are dystrophic in nature, often limiting the proliferation potential of affected cells in vivo and in vitro. Nevertheless, these lamin mutations, particularly in the . gene that encodes A-type lamins, have provided an interesting tool set to understand functions of nuclear intermediate filam

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Heinrich H. Bülthoff,Alexa I. Ruppertsbergwith the DNA associated protein, Barrier-to-Autointegration Factor (BAF). Most of the LEM proteins are integral proteins of the inner nuclear membrane and associate with the nuclear lamina, a structural scaffold of lamin intermediate filament proteins at the nuclear periphery, which is involved in n

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Zerebrale Blindheit und Gesichtsfeldausfälleor pRb and nuclear envelope breakdown in mitosis, many other nuclear envelope proteins influence the cell cycle through regulatory or structural functions. Of particular note among these are the nuclear envelope transmembrane proteins (NETs) that appear to influence cell cycle regulation through mul

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Methoden der kognitiven Neurowissenschaften mediated primarily through changes in gene expression. The evolution of the nuclear envelope and the consequent compartmentalization of the genome, which is a defining feature of eukaryotes, introduced a physical barrier to the free access of genes. Initially regarded as nothing more than this, a p

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obviate

Visuelle Wahrnehmung: Was, Wo und Wie,cellular organisms and in plants. Lamins form a proteinaceous meshwork that outlines the nucleoplasmic side of the inner nuclear membrane, while a small fraction of lamin molecules is also present in the nucleoplasm. They provide structural support for the nucleus and help regulate many other nuclea

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lambaste

Paul Hoff,Anastasia Theodoridouchromatin silencing, transcriptional regulation, and DNA damage repair. Nucleoporins, the structural components of the NPC, have been linked to a multitude of cancers through chromosomal translocations generating fusion proteins, changes in protein expression levels, and single point mutations. Only

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Neuropsychologie der Schizophrenierly during nuclear formation and has important roles during the eukaryotic cell cycle, where it regulates mitotic spindle assembly, nuclear envelope formation and cell cycle checkpoint control. Like other GTPases, Ran relies on the cycling between GTP-bound and GDP-bound conformations to interact wi