Titlebook: Calcium and Ion Channel Modulation; Alan D. Grinnell,David Armstrong,Meyer B. Jackson Book 1988 Plenum Press, New York 1988 DNA.activation

Mechanics

https://doi.org/10.1007/978-3-642-57521-1cky et al., 1985; Fedulova et al., 1985). Did all these channels evolve from the same precursor or was the Ca channel invented several times during phylogeny? To answer this question one needs to compare Ca channels from the most primitive organism known to have Ca currents with Ca channels from other “higher” organisms.

发怨言

边缘带来墨水

Dysarthria

Calcium Channels Incorporated into Planar Lipid Bilayers: Phenomenology, Pharmacology, and Phylogenycky et al., 1985; Fedulova et al., 1985). Did all these channels evolve from the same precursor or was the Ca channel invented several times during phylogeny? To answer this question one needs to compare Ca channels from the most primitive organism known to have Ca currents with Ca channels from other “higher” organisms.

Excitotoxin

Expression of Presynaptic Calcium Channels in , Oocytestage-dependent activation and inactivation properties) and sensitivity to pharmacological agents (especially dihydropyridines, w-conotoxin (wCgTx) and Cd ions). The type of Ca channel underlying synaptic transmission has not been established, although recent studies of mammalian neurons suggest that N-type channels are involved..

可行

Toward a Molecular Understanding of Synaptic Transmitter Release: Physiological Clues from the Squidthis presynaptic triggering action of Ca, none has emerged as a consensus favorite (Augustine, Charlton and Smith, 1987). This problem arises, in part, because there have been few attempts to test or evaluate these hypotheses.

嘲笑

intricacy

transdermal

Proton-Induced Transformation of Ca2+ Channel in Dorsal Root Ganglion Neuronsecularly identify Ca. channels are well underway (Borsotto et al., 1985; Ferry et al., 1985; Curtis & Catterall, 1984; Nakayama et al., 1987), their characterization in neuronal or muscular cells has been primarily based on their electrophysiological properties, gating, and ionic selectivity.

overshadow

Fura-2 Imaging of Localized Calcium Accumulation Within Squid ‘Giant’ Presynaptic Terminallkey, et al., 1978; Williams, et al., 1985; Tsien and Poenie, 1986) makes it important to know where Ca channels are located in the membrane of presynaptic terminals and to understand the propagation of Ca signals within presynaptic cytoplasm.