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Titlebook: Calcium Signaling Protocols; David G. Lambert Book 19991st edition Springer Science+Business Media New York 1999

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,‚Neue Medien ‘— Was ist das eigentlich?,tudies was performed by Hodgkin and Keynes (.) to measure the rate at which .Ca. labeled with .Ca. crosses the surface membrane of resting squid axons, or during nervous activity. In a few large excitable cells, it was also possible to measure Ca. entry indirectly through the measurement of inward c
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Gerhard Strube,Christoph Hölscherembrane down the steep concentration gradient (.–.). Ca. can enter through two main classes of plasma membrane-located Ca. channels: receptor operated and voltage sensitive (.–.). Voltage-sensitive Ca. channels are involved in a wide and diverse array of physiological responses including neurotransm
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G. Günter Voß,Werner Holly,Klaus Boehnkeing inositol phospholipid-specific phospholipase C (PLC). Activated PLC catalyzes the hydrolysis of phosphatidylinositol bisphosphate (PIP.), a minor membrane phospholipid, to form two second messengers, diacylglycerol (DAG) and inositol (1,4,5)trisphosphate [Ins(1,4,5,)P.]. DAG is a direct activato
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Neue Medien und kindliche Entwicklungroduce the second messengers, inositol(1,4,5)trisphosphate [Ins(1,4,5)P.] and diacylglycerol (.). Ins(1,4,5)P. interacts with specific receptor populations of ligand-gated channels to mobilize nonmitochondrial intracellular calcium (Ca.) stores (.). Because Ins(1,4,5)P. is very hydrophilic, it canno
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