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Titlebook: Calcium Channel Pharmacology; Stefan I. McDonough Book 2004 Kluwer Academic/Plenum Publishers, New York 2004 Calcium.Peptide.mutation.phar

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https://doi.org/10.1007/978-3-322-89441-0e the skeletal L-type calcium channel α., which is the only calcium channel that coordinates muscle contraction in skeletal muscle, and the L-type channel subtype α., whose expression seems to be restricted to retinaltissue.
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Modulation of High Voltage-Activated Calcium Channels by G Protein-Coupled Receptors,ling cascades are presented briefly. We examine the molecular determinants of Gβγ binding to presynaptic calcium channels and the modulation of Gβγ effects by other converging signaling pathways. Mechanisms for desensitization of GPCR activity and new evidence of receptor dimerization will be discussed.
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https://doi.org/10.1007/978-3-531-19795-1development. In certain instances, structural and functional differences generated by alternative splicing translate into unique pharmacological phenotypes. Pharmacologically distinct splice isoforms preferentially expressed in specific tissues or cell types offer exciting new targets for the design of highly specific drugs.
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Pharmacology of Cav1 (L-Type) Channels,lcium is a key physiological requirement for both sperm motility and the fertilization response, and calcium is a pathological contributor to cell death processes. Thus, in a very real sense we are conceived in a moment of calcium-mediated enthusiasm, we die from an excess of calcium and we are laid
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