Titlebook: Calcium Antagonists; A Critical Review Helmut Lydtin,Peter Trenkwalder Book 1990 Springer-Verlag Berlin Heidelberg 1990 Parkinson.anesthesi

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重叠

https://doi.org/10.1007/978-3-662-25277-2ion of verapamil, the successor compound gallopamil (D 600) shows a 3,4,5-trimethoxy substitution on the benzene ring. Both substances are optically active; according to recent investigations (Schrör 1985; Hugenholtz 1985), .(−)enantiomers of verapamil and gallopamil have a more powerful effect than the .(+)derivatives.

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Chemical Structure and Pharmacokinetics of Calcium Antagonists,ion of verapamil, the successor compound gallopamil (D 600) shows a 3,4,5-trimethoxy substitution on the benzene ring. Both substances are optically active; according to recent investigations (Schrör 1985; Hugenholtz 1985), .(−)enantiomers of verapamil and gallopamil have a more powerful effect than the .(+)derivatives.

Vaginismus

Physiological Significance of Calcium: Calcium Antagonism,nd its capacity to regulate cellular functions. Berridge (1985) even speaks, by analogy with cAMP, of calcium as a “second messenger” (e.g. in excitation-contraction coupling or insulin secretion). An up-to-date review of the “calcium messenger system” is provided by Rasmussen (1986).

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https://doi.org/10.1007/978-3-662-25277-2ion and atrial flutter) and hypertrophic cardiomyopathy. However, in contrast, the use of calcium antagonists as vasodilators in congestive heart failure and aortic regurgitation, and their use in heart surgery, coronary arteriography and coronary angioplasty remain relatively new indications.

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Indications for Calcium Antagonists,ion and atrial flutter) and hypertrophic cardiomyopathy. However, in contrast, the use of calcium antagonists as vasodilators in congestive heart failure and aortic regurgitation, and their use in heart surgery, coronary arteriography and coronary angioplasty remain relatively new indications.

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Physiological Significance of Calcium: Calcium Antagonism, array of enzymatic reactions, the metabolism of bone, electrical activation of various excitable cells, and the coupling of electrical activation to cellular secretion and muscular contraction (Antman et al. 1980). Katz (1985 c) distinguishes between structural functions of calcium (e.g. in bone) a