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Titlebook: CNS Complications of Malignant Disease; J. M. A. Whitehouse (Director of the CRC Medical O Book 1979 The contributors 1979 central nervous

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CNS Leukaemia in Blast Cell Crisis in CML and Philadelphia (Ph′) Positive Acute Lymphoid Leukaemiainical course and haematological findings are described in these patients. CNS leukaemia occurred between 5 and 11 months after diagnosis. Five out of the six cases had obtained remission with vincristine and prednisolone (V and P). Such patients should be treated as adult ALL and CNS prophylaxis should be given as soon as remission is achieved.
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Giuseppe Plazzi,Yves Dauvilliersophylaxis has been incorporated into their management by most workers. The frequency of CNS leukaemia is less certain in acute myelogenous leukaemia (AML) and there is no orthodox view upon its management, although it is probably becoming more frequent as remission rates rise and patients survive longer.
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Central Nervous System Involvement in Acute Myelogenous Leukaemiaophylaxis has been incorporated into their management by most workers. The frequency of CNS leukaemia is less certain in acute myelogenous leukaemia (AML) and there is no orthodox view upon its management, although it is probably becoming more frequent as remission rates rise and patients survive longer.
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