Titlebook: Bioinformatics Research and Applications; 20th International S Wei Peng,Zhipeng Cai,Pavel Skums Conference proceedings 2024 The Editor(s) (

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,FedKD-DTI: Drug-Target Interaction Prediction Based on Federated Knowledge Distillation,and time required for traditional high-throughput screening. However, DTI-related data are usually distributed across different institutions and their sharing is restricted because of data privacy and intellectual property rights. It is essential to construct a scheme that enhances multi-institution

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,Synthesis of Boolean Networks with Weak and Strong Regulators,and understand the dynamic nature of cell signaling events. Previously, automatic synthesis methods have been developed that consider a large set of Boolean networks and identify solutions that are consistent with all experimental data. A method and tool termed the Reasoning Engine (RE:IN) allows sy

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,Patch-Based Coupled Attention Network to Predict MSI Status in Colon Cancer,rker-related features from huge scale WSI images is a challenge faced by AI models. In this study, we propose a patch-based coupled attention neural network (CovAttnNet) designed to predict Microsatellite Instability (MSI) status from WSI images. CovAttnNet consists of a transformer based backbone n

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,DMSDR: Drug Molecule Synergy-Enhanced Network for Drug Recommendation with Multi-source Domain Knowing drugs by modeling patient electronic health records and drug side effects knowledge. However, they overlook the importance of drug synergy in drug recommendation, despite the fact that synergistic drug combinations can enhance therapeutic efficacy. To address this gap, we propose the Drug Molecu