Titlebook: Brain Tumor Stem Cells; Methods and Protocol Sheila K. Singh,Chitra Venugopal Book 2019 Springer Science+Business Media, LLC, part of Sprin

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Sheila K. Singh,Chitra VenugopalIncludes cutting-edge techniques for the study of brain tumor stem cell research.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts

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Sidra Mehtab,Jaydip Sen,Abhishek Duttares the history of normal and cancerous stem cells, and their implication in the current model of brain tumor development. The origins of stem cells date back to the 1960s, when they were first described as cells capable of self-renewal, extensive proliferation, and differentiation. Since then, many

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Shireen Fathima,Sheela Kiran Koreo the very dismal prognosis of this devastating disease. Consequently, this important population of cells needs to be further studied to uncover potential vulnerabilities, identify novel therapeutic targets, and develop drugs that can be translated to the clinic. One obstacle preventing progress in

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Uma N. Dulhare,Essam H. Housseinlation of cells. When experimental conditions are kept standard, these cells allow a high reproducibility of experimental findings from independent research groups. However, because these cell lines have been propagated in culture for decades, additional genetic lesions may be acquired leading to mo

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Machine Learning and Non-volatile Memoriesogy, disease modelling, and therapy development. Due to the transient nature of working with these cells, it is important to regularly confirm the cell status as a naive stem cell versus a more defined neural progenitor cell (NPC). Classically, this has been done using a panel of specific antibodies

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Wanli Chang,Nan Chen,Shuai Zhao,Xiaotian Daiem cells. A differentiation assay allows for study of one of the essential features of stem cells, the ability to differentiate into all of the cell types of its lineage, in order to ensure that the cells cultured and utilized in key experiments indeed have stem cell properties. Neural stem cells wh

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Wanli Chang,Nan Chen,Shuai Zhao,Xiaotian Dail prognosis. It is well established that tumor stem cells utilize the same available migratory machinery that normal cells employ. Some of the major determinants of brain tumor stem cell . are their cytoskeletal rearrangements and adhesion dynamics. This phenomenon allows brain tumor stem cells to p

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