Titlebook: Brain Glycogen Metabolism; Mauro DiNuzzo,Arne Schousboe Book 2019 Springer Nature Switzerland AG 2019 glycogen synthase.phosphorylase.ion

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Book 2019 understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive.Glycogen is the sole cerebral glucose reserve and is emerging as a fund

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Barbara Holshouser Ph.D.,Stephen Ashwal M.D.al conditions, when tissue energy demand is increased above baseline levels in the presence of normoglycemic concentrations of glucose. The signaling mechanism by which axons alert astrocytes to their increased energy requirement is likely to be elevated interstitial K., the inevitable consequence of increased neuronal activity.

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https://doi.org/10.1007/978-3-662-50468-0 how glycogen responds to selected behavioral, nutritional, environmental, hormonal, developmental and pathological conditions. We argue that interpreting glycogen metabolism through the lens of brain state is an effective approach to establish the relevance of energetics in connecting molecular and cellular neurophysiology to behavior.

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https://doi.org/10.1007/978-3-642-75525-5brief overview highlights some of the major advances in elucidation of glycogen’s roles in astrocytic functions and neurotransmission and the severe consequences of aberrant neuronal glycogen metabolism.

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Major Advances in Brain Glycogen Research: Understanding of the Roles of Glycogen Have Evolved frombrief overview highlights some of the major advances in elucidation of glycogen’s roles in astrocytic functions and neurotransmission and the severe consequences of aberrant neuronal glycogen metabolism.

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Optimum Procedure for the MRM Examination,sed, highlighting effects on the brain and discussing findings in genetically modified animal models that recapitulate these diseases. Finally, implications of glycogen synthesis in neurodegenerative and other diseases that impact the brain are presented.