Titlebook: Brain Dopaminergic Systems: Imaging with Positron Tomography; J. C. Baron,D. Comar,B. Mazoyer Book 1991 Springer Science+Business Media Do

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Investigation of the Dopamine System with Positron Emission Tomography: General Issues in Modellingimplementations of the standard three-compartment model proposed in the literature are compared within the frame of a common set of equations and parameters. Some considerations about model validation and PET experimental protocol optimization are discussed.

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Modelisation: Application to the D2 Receptors,Two kinds of graphical plots are applied to tissue and blood time activity data of (.F)-fluoroethylspiperone an irreversibly binding and (.C)-raclopride a reversibly binding D.- receptor ligand. A comparison of the two plots allows to check whether the asymptotic ratio between tissue and plasma acti

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