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Titlebook: Botulinum Toxin Therapy; Scott M. Whitcup,Mark Hallett Book 2021 Springer Nature Switzerland AG 2021 Botulinum toxin, toxin.Endopeptidase.

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Long Waves of Regional Developmentthe improvements in the manufacturing process, botulinum neurotoxins are still one of the most potent molecules and therefore, require special handing and additional safety/security measurements during production.
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Long Waves of Regional Developmentave been used or are being developed to further characterize the biology of toxins, to assist in vaccine production, to serve as delivery vehicles to neurons, and to be utilized as novel therapeutics for both neuronal and non-neuronal cells.
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https://doi.org/10.1007/978-3-662-67504-5tients with focal dystonias botulinum toxin ameliorates sensory disturbances, including reduced spatial discrimination acuity and pain. Overall, these observations suggest that in these patients botulinum toxin-induced effects encompass complex mechanisms beyond chemodenervation of the injected musc
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https://doi.org/10.1007/978-1-935704-34-8al-life studies. OnabotA is a safe and efficacious treatment for chronic migraine and possibly high-frequency episodic migraine. Further research is still needed to understand its mechanism of action to fully develop its therapeutic potential.
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https://doi.org/10.1007/978-1-4899-1228-2that peripherally administered BoNT-A reaches the CNS by axonal transport. There is increasing evidence that BoNT-A is preventing pain in a growing range of disorders. In the absence of unexpected findings, or an increase in the uncontrolled use of illicit preparations by uneducated persons, BoNT-A
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