| 期刊全称 | Bone Toxicology | | 影响因子2023 | Susan Y. Smith,Aurore Varela,Rana Samadfam | | 视频video | | | 发行地址 | Comparative bone biology of animal species commonly used in toxicology studies with humans.Special considerations highlighted for Juvenile toxicology.Collection of chapters on bone interactions with o | | 学科分类 | Molecular and Integrative Toxicology | | 图书封面 |  | | 影响因子 | The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describes our current understanding of bone biology and its primary regulatory pathways. Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to juvenile toxicology studies. This is intended to address recent regulatory requirements to evaluate skeletal development for drugs in development for pediatric populations. The second part of the book describes the principal techniques and methods used in bone research; understanding how these end-points are derived is fundamental to their appropriate application. These first two parts of the book provide thebackground and the means to develop the concepts in part three which describes bone and its interaction with other organ systems. The unique series of chapters in part three, contributed to by key leaders in their respective fiel | | Pindex | Book 2017 |
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发表于 2025-3-21 18:06:13
