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Titlebook: Bone Regulators and Osteoporosis Therapy; Paula H. Stern Book 2020 Springer Nature Switzerland AG 2020 Bone.Bone cell regulators.Osteoporo

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Liver Ischaemia-Reperfusion Injurycts the amount and structure of bone, as well as its quality. These qualities are determined and maintained by osteoblasts (bone-forming cells) and osteoclasts (bone-resorbing cells) on the surface of the bone and osteocytes embedded within the bone matrix. Bone development and growth also involves
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Vascular Disorders of the Livertracellular calcium and phosphate metabolism and in controlling skeletal growth and repair. Acting through complex signaling mechanisms that in many instances proceed in a tissue-specific manner, precise control of these processes is achieved. A variety of direct and indirect disease processes, alon
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Bile Acid Sulfation and Cholestasis,ing (osteoblast) lineage and the bone-resorbing (osteoclast) lineage. The inducible cyclooxygenase, COX-2, is largely responsible for most PGE. production in bone, and once released, PGE. is rapidly degraded in vivo. COX-2 is induced by multiple agonists – hormones, growth factors, and proinflammato
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Laurence Tabone,Pierre Teira,Annie Lavoie However, an ever-expanding number of these factors have been discovered to have major effects on bone cells and the development of the skeleton in health and disease (Table .). In addition, several cytokines have been directly linked to the development of osteoporosis in both animal models and in p
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