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Titlebook: Bone Morphogenetic Proteins; From Laboratory to C Slobodan Vukicevic,Kuber T. Sampath Book 2002 Springer Basel AG 2002 biochemistry.biology

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Prostate-derived factor and growth and differentiation factor-8: newly discovered members of the TGnic development, as well as in adult life. This superfamily in addition to TGF-βs also contains the inhibins, activins, Mullerian inhibiting substance, and bone morphogenetic proteins (BMPs), as well as the various growth and differentiation factors (GDFs). Members of the TGF-β superfamily are highl
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Preclinical models of recombinant BMP induced healing of orthopedic defects,rtant part of the therapeutic approach to bone defects is the implantation of materials that support new bone formation. Such implants may hasten healing by three mechanisms: osteoconduction, osteogenesis, and osteoinduction [.]–[.]. In osteoconduction, the implanted material serves as an inert scaf
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Osteogenic protein-1 (OP-1, BMP-7) for stimulation of healing of closed fractures: evidence based mwly as fractures located in other places in the human body. Fractures of the lower extremity often occur due to high-energy trauma such as motor vehicle accidents. Consequently, the average age of the patients is generally low, with a high incidence at the age of 30 years. Therefore, most patients a
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Maxillofacial reconstruction,iplinary cranial base interventions, from congenital malformations to acquired traumatic or tumor related defects. In most applications the autogenous bone graft is the clinical gold standard. These grafts range from small intraorally harvested bone particles to large composite vascularized bone fla
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Bone morphogenetic proteins in periodontal regeneration,l reconstruction includes regeneration of a variety of tissues including cementum, periodontal ligament, alveolar bone and gingiva. Wound healing is thought to be regulated by various growth and differentiation factors, such as bone morphogenetic proteins (BMPs), and cytokines. The expression of the
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Evaluation of OP-1 in a rabbit model of lumbar fusions, thousand spinal fusions are performed each year in the United States alone. There are different types of lumbar fusion with posterolateral intertransverse fusion using iliac crest autograft being the most common. This type of fusion is used in the treatment of a wide variety of conditions including
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