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Titlebook: Bone Morphogenetic Proteins; From Laboratory to C Slobodan Vukicevic,Kuber T. Sampath Book 2002 Springer Basel AG 2002 biochemistry.biology

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978-3-0348-9446-3Springer Basel AG 2002
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Bone Morphogenetic Proteins978-3-0348-8121-0Series ISSN 1422-7746 Series E-ISSN 2296-4525
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Manuela Limbeek,Mariëlle Bruninghe concept that there is some substance naturally present in bone, which is responsible for the regeneration and repair activity. He called this substance bone morphogenetic protein (BMP) and initiated a search for these molecules.
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1422-7746 tic proteins (BMPs) are summarized in this topical volume. Distinguished scientists present reviews on a range of scientific topics, including biochemistry, biology, molecular biology and preclinical animal studies on spinal fusion, cartilage repair, craniofacial and dental reconstruction using BMPs
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Osteogenic protein-1 (OP-1) in the repair of bone defects and fractures of long bones: clinical expcapacity to induce bone formation [., .]. Subsequently, extensive preclinical and clinical research has confirmed the efficacy as well as safety of OP-1 in the process of bone repair and regeneration [.–.]. This paper will focus on clinical experience with OP-1 in the treatment of nonunions of the appendicular skeleton.
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