Titlebook: Blood-Brain Barrier; Drug Delivery and Br David Kobiler,Shlomo Lustig,Shlomo Shapira Book 2001 Springer Science+Business Media New York 200

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Limit Theorems for Large Deviationstely spread to distant target tissues, such as the central nervous system (CNS). Viral infections of the nervous system are amongst the most severe and potentially devastating of human infections. The outcome of such infection is determined in part by the type of cells infected in the CNS, with most

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Mathematics and its Applicationsnfection. Many mice are spontaneously able to efficiently activate these host responses and limit viral replication, leading to survival. Other individuals develop pathologies including infection of a central regulatory region of the CNS, the .,infection of the lumbar sacral spinal cord (leading to

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Renewal Theorem For Markov Chains Theorem D,angeli .,1994), therapy of salivary carcinomas (Samuelson, 1996) and secretion of therapeutic proteins such as growth factors, enzymes and antigens (Barka, 1996). The salivary glands hold several advantages for gene transfer: salivary cells are designed to synthesize and secrete abundant quantities