Titlebook: Blood Substitutes and Oxygen Biotherapeutics; Henry Liu,Alan D. Kaye,Jonathan S. Jahr Book 2022 The Editor(s) (if applicable) and The Auth

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The Global Burden of Anemiarrogate marker for red blood cell mass, with anemia typically being defined by a hemoglobin concentration less than 13 g/dL in adult men and less than 12 g/dL in adult, non-pregnant women. Anemia is remarkably common globally, though low- and middle-income countries bear the greatest burden. Anemia

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Blood Component Therapy: The History, Efficacy, and Adverse Effects in Clinical Practice transfusion was obstetrical hemorrhage. Blood banking was initiated in Russia and the first blood bank in the United States was at Chicago’s Cook County Hospital in 1937. These whole blood transfusions were, for the most part hemostatic. Dr. Jose Antonio Grifos Lucas pioneered the technique of aphe

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Allogeneic Blood Transfusion: Complications and Side Effects that is transfused, the patient is at risk of multiple types of complications, which vary greatly in terms of frequency and severity. As a result of exquisitely sensitive testing, the incidence transmission of hepatitis and HIV from transfusion has been reduced to near zero. Conversely, the inciden

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Nitric Oxide and Hemoglobin: Physiological Implicationsn the formation of nitrate when hemoglobin is oxygenated. This is referred to as the dioxygenation reaction. Because nitrate is biologically inert at the concentrations reached during the dioxygenation reaction, it was thought that hemoglobin would only inhibit NO signaling. However, hemoglobin can

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