Titlebook: Blood Substitutes; Physiological Basis R. M. Winslow,K. D. Vandegriff,M. Intaglietta Book 1995 Birkhäuser Boston 1995 Biologie.Medizin.bio

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A Theoretical Analysis of Oxygen Transport: A New Strategy for the Design of Hemoglobin-Based Red Cthan it is from red blood cells. On first consideration, this appears to be advantageous, but new data obtained by direct measurements in the microcirculation indicate that facilitated release may actually lead to an autoregulatory decrease in capillary perfusion. This leads to the conclusion that t

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,Microcirculatory Consequences of Blood Substitution with αα-Hemoglobin,icrocirculation and the balance between diffusive and convective oxygen transport. When blood volume is maintained with either crystalloid or colloidal volume replacement, microcirculatory oxygen transport is adequate for red blood cell losses of the order of 60%. Hemoglobin solutions utilizing αα-h

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Sample Cells, Filters and Solvents,iven patient should be based on the need for transfusion, not just on an estimation of the risks. Transfusion requirements need to be understood on physiological grounds, but there is no clear-cut “transfusion trigger” that emerges from this understanding. Rather, the clinician must combine physiolo

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https://doi.org/10.1007/978-3-540-71951-9ansport products has solved many of the problems of Fluosol DA® including PFC concentration, elimination of surfactant side effects and improved storage stability. Some side effects, most notably, thrombocytopenia and flu-like symptoms still remain to be solved. Two new oxygen transport formulations

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Commercial Light Scattering Instruments,atives are prepared by treatment of hemoglobin with some chemical reagent to yield a product that possesses a property considered desirable for a blood substitute. The degree of sophistication of these derivatives has, in general, increased in proportion to our knowledge of hemoglobin itself.

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