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Titlebook: Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis and Pharmacotherapy; Carlos A. Zarate,Husseini K. Manji Book 20091st editio

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期刊全称Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis and Pharmacotherapy
影响因子2023Carlos A. Zarate,Husseini K. Manji
视频video
发行地址Comprehensive volume covering neurobiology, clinical results and the development of novel therapeutics.Edited by leading experts in the field.International authorship.Includes supplementary material:
学科分类Milestones in Drug Therapy
图书封面Titlebook: Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis and Pharmacotherapy;  Carlos A. Zarate,Husseini K. Manji Book 20091st editio
影响因子.Although our knowledge of mood disorders is expanding, comparatively little is known about bipolar depression in particular. This book offers the most up-to-date information about the diagnosis, treatment, and research surrounding bipolar depression...Early chapters provide diagnostic information and review the course, outcome and genetics of this heritable condition. The book gives a thorough and unique overview of the neurobiology of the disorder, including neuroimaging work. Several chapters delineate the treatment of bipolar depression in special populations such as children and pregnant women. Furthermore, the particular issues of suicide, focusing on the need for assessment during both acute and maintenance treatment, are addressed. Finally, acute and long-term treatment strategies for bipolar depression are discussed, including both traditional and novel therapeutics, as well as non-pharmacological treatments...This volume offers researchers and clinicians key insights into this devastating disorder..
Pindex Book 20091st edition
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Neuroimaging studies of bipolar depression: therapeutic implications and basal ganglia white matter, and enlargement of the third and lateral ventricles are likely associated with cerebrovascular disease. Mood stabilizers and antidepressant drugs may attenuate pathological limbic activity, and increase neurotrophic processes, restoring balance to the system.
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Non-pharmacological somatic treatments for bipolar depressionment of new forms of convulsive therapy, particularly Magnetic Seizure Therapy (MST) and Focal Electrically Administered Seizure Therapy (FEAST). Additional novel interventions such as repetitive transcranial magnetic stimulation (rTMS), deep brain stimulation (DBS), and vagus nerve stimulation (VNS
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Late-onset bipolar disorderons for late-life BPD are not currently available. Therefore, extrapolation from trials in mixed-age populations and adaptation to the older patient is necessary to establish treatment recommendations.
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