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Titlebook: Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2; Susanne Zeilinger,Juan-Francisco Martín,Carlos Gar Book 201

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期刊全称Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2
影响因子2023Susanne Zeilinger,Juan-Francisco Martín,Carlos Gar
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发行地址Up-to-date information on fungal secondary metabolism covering recent advancements in genomics and metabolomics.Book chapters written by top scientists, providing a cutting-edge point of view.Scientif
学科分类Fungal Biology
图书封面Titlebook: Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2;  Susanne Zeilinger,Juan-Francisco Martín,Carlos Gar Book 201
影响因子​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the mos
Pindex Book 2015
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https://doi.org/10.1057/9780230590427om reductionist to holistic approaches for the study of filamentous fungi can be observed currently. This development is also reflected by the emergence of metabolomics as the latest of the so-called -omics disciplines. Metabolomics, the scientific discipline dealing with the determination of the lo
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